Gabapentin (aggiornato al 8/1/2020)

A cura di Alessandra Russo. Specialista in Tossicologia Medica. Messina

 

Principio attivo

Effetto

Antiacidi (1)

Possibile riduzione dell’efficacia del gabapentin

Ginkgo (2-4)

Possibile riduzione dell’efficacia del gabapentin

Morfina (5,6)

Possibile aumento delle concentrazioni plasmatiche di gabapentin

Orlistat (7)

Possibile riduzione dell’efficacia del gabapentin

 

Bibliografia

  1. Product Information: Neurontin(R), gabapentin. Pfizer, Inc., New York, NY, 05/2002.
  2. Arenz A, et al. Occurrence of neurotoxic 4′-0-methylpyridoxine in Ginkgo biloba leaves, Ginkgo medications and Japanese Ginkgo food. Planta Medica 1996; 62: 548-551.
  3. Granger AS. Ginkgo biloba precipitating epileptic seizures. Age Ageing 2001; 30: 523-525.
  4. Yagi M, et al. Studies on the constituents of edible and medicinal plants. IV. Determination of 4′-O-methylpyridoxine in serum of the patient with Gin-nan food poisoning. Yakugaku Zasshi 1993; 113: 596-99.
  5. Product Information: GRALISE(R) oral tablets, gabapentin oral tablets. Abbott Laboratories, North Chicago, IL, Jan, 2011.
  6. Product Information: Neurontin(R) oral capsules, tablets, solution, gabapentin oral capsules, tablets, solution. Parke-Davis, New York, NY, Jul, 2010.
  7. Product Information: XENICAL(R) oral capsules, orlistat oral capsules. Genentech USA Inc. (per FDA), South San Francisco, CA, Oct, 2013.

 

Link

Ultimo aggiornamento: 04 febbraio 2020